CRISPR-Cas9 Direct Fusions for Improved Genome Editing via Enhanced Homologous Recombination

DNA repair in mammalian cells involves the coordinated action of a range of complex cellular repair machinery. Our understanding of these DNA repair processes has advanced to the extent that they can be leveraged to improve the efficacy and precision of Cas9-assisted genome editing tools. Here, we r...

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Detalles Bibliográficos
Autores principales: Tabassum, Tahmina, Pietrogrande, Giovanni, Healy, Michael, Wolvetang, Ernst J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572186/
https://www.ncbi.nlm.nih.gov/pubmed/37834150
http://dx.doi.org/10.3390/ijms241914701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572186/
https://www.ncbi.nlm.nih.gov/pubmed/37834150
http://dx.doi.org/10.3390/ijms241914701

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