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CRISPR-Cas9 Direct Fusions for Improved Genome Editing via Enhanced Homologous Recombination
DNA repair in mammalian cells involves the coordinated action of a range of complex cellular repair machinery. Our understanding of these DNA repair processes has advanced to the extent that they can be leveraged to improve the efficacy and precision of Cas9-assisted genome editing tools. Here, we r...
Autores principales: | Tabassum, Tahmina, Pietrogrande, Giovanni, Healy, Michael, Wolvetang, Ernst J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572186/ https://www.ncbi.nlm.nih.gov/pubmed/37834150 http://dx.doi.org/10.3390/ijms241914701 |
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