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Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding

Platelets are generated by specialized cells called megakaryocytes (MKs). However, MK’s origin and platelet release mode have remained incompletely understood. Here, we established direct visualization of embryonic thrombopoiesis in vivo by combining multiphoton intravital microscopy (MP-IVM) with a...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Ishikawa-Ankerhold, Hellen, Winterhalter, Julia, Lorenz, Michael, Vladymyrov, Mykhailo, Massberg, Steffen, Schulz, Christian, Orban, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572188/
https://www.ncbi.nlm.nih.gov/pubmed/37830625
http://dx.doi.org/10.3390/cells12192411