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Normalization of the ATP1A1 Signalosome Rescinds Epigenetic Modifications and Induces Cell Autophagy in Hepatocellular Carcinoma †

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. In metabolic dysfunction-associated steatohepatitis (MASH)-related HCC, cellular redox imbalance from metabolic disturbances leads to dysregulation of the α1-subunit of the Na/K-ATPase (ATP1A1) signalosome....

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Detalles Bibliográficos
Autores principales: Rajan, Pradeep Kumar, Udoh, Utibe-Abasi S., Nakafuku, Yuto, Pierre, Sandrine V., Sanabria, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572209/
https://www.ncbi.nlm.nih.gov/pubmed/37830582
http://dx.doi.org/10.3390/cells12192367