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Vanadium Pentoxide Exposure Causes Strain-Dependent Changes in Mitochondrial DNA Heteroplasmy, Copy Number, and Lesions, but Not Nuclear DNA Lesions

Interstitial lung diseases (ILDs) are lethal lung diseases characterized by pulmonary inflammation and progressive lung interstitial scarring. We previously developed a mouse model of ILD using vanadium pentoxide (V(2)O(5)) and identified several gene candidates on chromosome 4 associated with pulmo...

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Detalles Bibliográficos
Autores principales: Dobson, Nick L., Kleeberger, Steven R., Burkholder, Adam B., Walters, Dianne M., Gladwell, Wesley, Gerrish, Kevin, Vellers, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572248/
https://www.ncbi.nlm.nih.gov/pubmed/37833956
http://dx.doi.org/10.3390/ijms241914507