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Pseudotyping Improves the Yield of Functional SARS-CoV-2 Virus-like Particles (VLPs) as Tools for Vaccine and Therapeutic Development

Virus-like particles (VLPs) have been proposed as an attractive tool in SARS-CoV-2 vaccine development, both as (1) a vaccine candidate with high immunogenicity and low reactogenicity and (2) a substitute for live virus in functional and neutralization assays. Though multiple SARS-CoV-2 VLP designs...

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Detalles Bibliográficos
Autores principales: Zak, Andrew J., Hoang, Trang, Yee, Christine M., Rizvi, Syed M., Prabhu, Ponnandy, Wen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572262/
https://www.ncbi.nlm.nih.gov/pubmed/37834067
http://dx.doi.org/10.3390/ijms241914622