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MiR-148a-3p within HucMSC-Derived Extracellular Vesicles Suppresses Hsp90b1 to Prevent Fibroblast Collagen Synthesis and Secretion in Silica-Induced Pulmonary Fibrosis

Silicosis is a fatal occupational respiratory disease caused by the prolonged inhalation of respirable silica. The core event of silicosis is the heightened activity of fibroblasts, which excessively synthesize extracellular matrix (ECM) proteins. Our previous studies have highlighted that human umb...

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Detalles Bibliográficos
Autores principales: Jiang, Qiyue, Zhao, Jing, Jia, Qiyue, Wang, Hongwei, Xue, Wenming, Ning, Fuao, Wang, Jiaxin, Wang, Yan, Zhu, Zhonghui, Tian, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572270/
https://www.ncbi.nlm.nih.gov/pubmed/37833927
http://dx.doi.org/10.3390/ijms241914477