(+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis

Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of lipids within hepatocytes, which compromises liver functionality following mitochondrial dysfunction and increased production of reactive oxygen species (ROS). Lipoic acid is one of the prosthetic groups of the pyruvat...

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Detalles Bibliográficos
Autores principales: Longhitano, Lucia, Distefano, Alfio, Amorini, Angela Maria, Orlando, Laura, Giallongo, Sebastiano, Tibullo, Daniele, Lazzarino, Giuseppe, Nicolosi, Anna, Alanazi, Amer M., Saoca, Concetta, Macaione, Vincenzo, Aguennouz, M’hammed, Salomone, Federico, Tropea, Emanuela, Barbagallo, Ignazio Alberto, Volti, Giovanni Li, Lazzarino, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572323/
https://www.ncbi.nlm.nih.gov/pubmed/37833939
http://dx.doi.org/10.3390/ijms241914491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572323/
https://www.ncbi.nlm.nih.gov/pubmed/37833939
http://dx.doi.org/10.3390/ijms241914491

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