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(+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of lipids within hepatocytes, which compromises liver functionality following mitochondrial dysfunction and increased production of reactive oxygen species (ROS). Lipoic acid is one of the prosthetic groups of the pyruvat...
Autores principales: | Longhitano, Lucia, Distefano, Alfio, Amorini, Angela Maria, Orlando, Laura, Giallongo, Sebastiano, Tibullo, Daniele, Lazzarino, Giuseppe, Nicolosi, Anna, Alanazi, Amer M., Saoca, Concetta, Macaione, Vincenzo, Aguennouz, M’hammed, Salomone, Federico, Tropea, Emanuela, Barbagallo, Ignazio Alberto, Volti, Giovanni Li, Lazzarino, Giacomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572323/ https://www.ncbi.nlm.nih.gov/pubmed/37833939 http://dx.doi.org/10.3390/ijms241914491 |
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