Effect of Food on the Pharmacokinetics of Tenofovir Amibufenamide: A Phase I, Randomized, Open-Label, Two-Period Crossover Trial in Healthy Adult Subjects

PURPOSE: Tenofovir amibufenamide (TMF) is a novel nucleotide reverse transcriptase inhibitor. The aim of this study was to investigate the effect of food on the single-dose pharmacokinetic properties of TMF. PATIENTS AND METHODS: In this open-label, randomized, crossover study, after an overnight fa...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Wu, Minglan, Kai, Jiejing, Lin, Meihua, Zheng, Yunliang, Jiang, Yiya, Huang, Qian, Zhai, You, Qiu, Yunqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572397/
https://www.ncbi.nlm.nih.gov/pubmed/37840641
http://dx.doi.org/10.2147/DDDT.S419084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572397/
https://www.ncbi.nlm.nih.gov/pubmed/37840641
http://dx.doi.org/10.2147/DDDT.S419084

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