The Potential of JAG Ligands as Therapeutic Targets and Predictive Biomarkers in Multiple Myeloma

The NOTCH ligands JAG1 and JAG2 have been correlated in vitro with multiple myeloma (MM) cell proliferation, drug resistance, self-renewal and a pathological crosstalk with the tumor microenvironment resulting in angiogenesis and osteoclastogenesis. These findings suggest that a therapeutic approach...

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Detalles Bibliográficos
Autores principales: Platonova, Natalia, Lazzari, Elisa, Colombo, Michela, Falleni, Monica, Tosi, Delfina, Giannandrea, Domenica, Citro, Valentina, Casati, Lavinia, Ronchetti, Domenica, Bolli, Niccolò, Neri, Antonino, Torricelli, Federica, Crews, Leslie A., Jamieson, Catriona H. M., Chiaramonte, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572399/
https://www.ncbi.nlm.nih.gov/pubmed/37834003
http://dx.doi.org/10.3390/ijms241914558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572399/
https://www.ncbi.nlm.nih.gov/pubmed/37834003
http://dx.doi.org/10.3390/ijms241914558

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