Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury

Acute kidney injury (AKI) is a common and serious disease with high morbidity and mortality, and its pathophysiological mechanisms are not fully understood. Increasing evidence suggests an important role of ferroptosis in AKI. Krüppel-like factor 15 (KLF15) is a transcription factor involved in seve...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Dong, Shihui, Fan, Yun, Xia, Yuanyuan, Yang, Fan, Chen, Zhaohong, Chen, Dacheng, Zhang, Mingchao, Liang, Dandan, Zeng, Caihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572468/
https://www.ncbi.nlm.nih.gov/pubmed/37833977
http://dx.doi.org/10.3390/ijms241914530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572468/
https://www.ncbi.nlm.nih.gov/pubmed/37833977
http://dx.doi.org/10.3390/ijms241914530

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