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Low Levels of Amyloid Precursor Protein (APP) Promote Neurogenesis and Decrease Gliogenesis in Human Neural Stem Cells

Amyloid precursor protein (APP) has been widely studied due to its association with Alzheimer’s disease (AD). However, the physiological functions of APP are still largely unexplored. APP is a transmembrane glycoprotein whose expression in humans is abundant in the central nervous system. Specifical...

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Detalles Bibliográficos
Autores principales: Coronel, Raquel, López-Alonso, Victoria, Gallego, Marta I., Liste, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572469/
https://www.ncbi.nlm.nih.gov/pubmed/37834082
http://dx.doi.org/10.3390/ijms241914635