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Exploring PCSK9 Genetic Impact on Lipoprotein(a) via Dual Approaches: Association and Mendelian Randomization

Previous investigations have suggested an association between the PCSK9 common polymorphism E670G and Lipoprotein(a) (Lp(a)) levels, as well as a link between plasma PCSK9 levels and Lp(a) concentrations. However, the causal relationship between plasma PCSK9 and Lp(a) levels remains uncertain. In th...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Ching, Hsu, Lung-An, Ko, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572552/
https://www.ncbi.nlm.nih.gov/pubmed/37834124
http://dx.doi.org/10.3390/ijms241914668