Design, Synthesis, and Potent Anticancer Activity of Novel Indole-Based Bcl-2 Inhibitors

The Bcl-2 family plays a crucial role in regulating cell apoptosis, making it an attractive target for cancer therapy. In this study, a series of indole-based compounds, U1–6, were designed, synthesized, and evaluated for their anticancer activity against Bcl-2-expressing cancer cell lines. The bind...

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Detalles Bibliográficos
Autores principales: Almehdi, Ahmed M., Soliman, Sameh S. M., El-Shorbagi, Abdel-Nasser A., Westwell, Andrew D., Hamdy, Rania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572575/
https://www.ncbi.nlm.nih.gov/pubmed/37834104
http://dx.doi.org/10.3390/ijms241914656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572575/
https://www.ncbi.nlm.nih.gov/pubmed/37834104
http://dx.doi.org/10.3390/ijms241914656

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