Evaluation of the Polygenic Risk Score for Alzheimer’s Disease in Russian Patients with Dementia Using a Low-Density Hydrogel Oligonucleotide Microarray

The polygenic risk score (PRS), together with the ɛ4 allele of the APOE gene (APOE-ɛ4), has shown high potential for Alzheimer’s disease (AD) risk prediction. The aim of this study was to validate the model of polygenic risk in Russian patients with dementia. A microarray-based assay was developed t...

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Detalles Bibliográficos
Autores principales: Ikonnikova, Anna, Morozova, Anna, Antonova, Olga, Ochneva, Alexandra, Fedoseeva, Elena, Abramova, Olga, Emelyanova, Marina, Filippova, Marina, Morozova, Irina, Zorkina, Yana, Syunyakov, Timur, Andryushchenko, Alisa, Andreuyk, Denis, Kostyuk, Georgy, Gryadunov, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572681/
https://www.ncbi.nlm.nih.gov/pubmed/37834213
http://dx.doi.org/10.3390/ijms241914765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572681/
https://www.ncbi.nlm.nih.gov/pubmed/37834213
http://dx.doi.org/10.3390/ijms241914765

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