Development of Engineered-U1 snRNA Therapies: Current Status

Splicing of pre-mRNA is a crucial regulatory stage in the pathway of gene expression. The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Targeting aberrant RNA(s) may thus provide an op...

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Detalles Bibliográficos
Autores principales: Gonçalves, Mariana, Santos, Juliana Inês, Coutinho, Maria Francisca, Matos, Liliana, Alves, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572768/
https://www.ncbi.nlm.nih.gov/pubmed/37834063
http://dx.doi.org/10.3390/ijms241914617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572768/
https://www.ncbi.nlm.nih.gov/pubmed/37834063
http://dx.doi.org/10.3390/ijms241914617

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