An Intrabody against B-Cell Receptor-Associated Protein 31 (BAP31) Suppresses the Glycosylation of the Epithelial Cell-Adhesion Molecule (EpCAM) via Affecting the Formation of the Sec61-Translocon-Associated Protein (TRAP) Complex

The epithelial cell-adhesion molecule (EpCAM) is hyperglycosylated in carcinoma tissue and the oncogenic function of EpCAM primarily depends on the degree of glycosylation. Inhibiting EpCAM glycosylation is expected to have an inhibitory effect on cancer. We analyzed the relationship of BAP31 with 8...

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Detalles Bibliográficos
Autores principales: Wang, Tianyi, Wang, Changli, Wang, Jiyu, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572819/
https://www.ncbi.nlm.nih.gov/pubmed/37834237
http://dx.doi.org/10.3390/ijms241914787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572819/
https://www.ncbi.nlm.nih.gov/pubmed/37834237
http://dx.doi.org/10.3390/ijms241914787

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