Differential Effects of Hypothermia and SZR72 on Cerebral Kynurenine and Kynurenic Acid in a Piglet Model of Hypoxic–Ischemic Encephalopathy

Kynurenic acid (KYNA), an endogenous neuroprotectant with antiexcitotoxic, antioxidant, and anti-inflammatory effects, is synthesized through the tryptophan-kynurenine (KYN) pathway. We investigated whether brain KYN or KYNA levels were affected by asphyxia in a translational piglet model of hypoxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Domoki, Ferenc, Tóth-Szűki, Valéria, Kovács, Viktória, Remzső, Gábor, Körmöczi, Tímea, Vécsei, László, Berkecz, Róbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572886/
https://www.ncbi.nlm.nih.gov/pubmed/37833970
http://dx.doi.org/10.3390/ijms241914522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572886/
https://www.ncbi.nlm.nih.gov/pubmed/37833970
http://dx.doi.org/10.3390/ijms241914522

Ejemplares similares