The Dual Role of the Innate Immune System in the Effectiveness of mRNA Therapeutics

Advances in molecular biology have revolutionized the use of messenger RNA (mRNA) as a therapeutic. The concept of nucleic acid therapy with mRNA originated in 1990 when Wolff et al. reported successful expression of proteins in target organs by direct injection of either plasmid DNA or mRNA. It too...

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Detalles Bibliográficos
Autores principales: Muslimov, Albert, Tereshchenko, Valeriy, Shevyrev, Daniil, Rogova, Anna, Lepik, Kirill, Reshetnikov, Vasiliy, Ivanov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573212/
https://www.ncbi.nlm.nih.gov/pubmed/37834268
http://dx.doi.org/10.3390/ijms241914820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573212/
https://www.ncbi.nlm.nih.gov/pubmed/37834268
http://dx.doi.org/10.3390/ijms241914820

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