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Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation

Hepatic stellate cells (HSCs) are the main contributors to the development and progression of liver fibrosis. Parkin is an E3 ligase involved in mitophagy mediated by lysosomes that maintains mitochondrial homeostasis. Unfortunately, there is little information regarding the regulation of parkin by...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyun, Kim, Kyu Min, Jung, Eun Hee, Lee, Hye Rim, Yang, Ji Hye, Cho, Sam Seok, Ki, Sung Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573240/
https://www.ncbi.nlm.nih.gov/pubmed/37834275
http://dx.doi.org/10.3390/ijms241914826