Cargando…
Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation
Hepatic stellate cells (HSCs) are the main contributors to the development and progression of liver fibrosis. Parkin is an E3 ligase involved in mitophagy mediated by lysosomes that maintains mitochondrial homeostasis. Unfortunately, there is little information regarding the regulation of parkin by...
Autores principales: | Lee, Ji Hyun, Kim, Kyu Min, Jung, Eun Hee, Lee, Hye Rim, Yang, Ji Hye, Cho, Sam Seok, Ki, Sung Hwan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573240/ https://www.ncbi.nlm.nih.gov/pubmed/37834275 http://dx.doi.org/10.3390/ijms241914826 |
Ejemplares similares
-
Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells
por: Kim, Ji Young, et al.
Publicado: (2020) -
MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy
por: Dou, Shi-Ying, et al.
Publicado: (2021) -
Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53
por: Song, Young Mi, et al.
Publicado: (2016) -
Src Inhibition Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation and Decreasing Connective Tissue Growth Factor
por: Seo, Hye-Young, et al.
Publicado: (2020) -
Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy
por: Kim, Seong-Jun, et al.
Publicado: (2013)