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Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies

Phenylpyrazolo[3,4-d]pyrimidine is considered a milestone scaffold known to possess various biological activities such as antiparasitic, antifungal, antimicrobial, and antiproliferative activities. In addition, the urgent need for selective and potent novel anticancer agents represents a major route...

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Detalles Bibliográficos
Autores principales: Aljohani, Ahmed K. B., El Zaloa, Waheed Ali Zaki, Alswah, Mohamed, Seleem, Mohamed A., Elsebaei, Mohamed M., Bayoumi, Ashraf H., El-Morsy, Ahmed M., Almaghrabi, Mohammed, Awaji, Aeshah A., Hammad, Ali, Alsulaimany, Marwa, Ahmed, Hany E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573254/
https://www.ncbi.nlm.nih.gov/pubmed/37834474
http://dx.doi.org/10.3390/ijms241915026