Loss of Key EMT-Regulating miRNAs Highlight the Role of ZEB1 in EGFR Tyrosine Kinase Inhibitor-Resistant NSCLC

Despite recent advances in the treatment of non-small cell lung cancer (NSCLC), acquired drug resistance to targeted therapy remains a major obstacle. Epithelial-mesenchymal transition (EMT) has been identified as a key resistance mechanism in NSCLC. Here, we investigated the mechanistic role of key...

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Detalles Bibliográficos
Autores principales: Gohlke, Linus, Alahdab, Ahmad, Oberhofer, Angela, Worf, Karolina, Holdenrieder, Stefan, Michaelis, Martin, Cinatl, Jindrich, Ritter, Christoph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573279/
https://www.ncbi.nlm.nih.gov/pubmed/37834189
http://dx.doi.org/10.3390/ijms241914742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573279/
https://www.ncbi.nlm.nih.gov/pubmed/37834189
http://dx.doi.org/10.3390/ijms241914742

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