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Recoding UAG to selenocysteine in Saccharomyces cerevisiae

Unique chemical and physical properties are introduced by inserting selenocysteine (Sec) at specific sites within proteins. Recombinant and facile production of eukaryotic selenoproteins would benefit from a yeast expression system; however, the selenoprotein biosynthetic pathway was lost in the evo...

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Detalles Bibliográficos
Autores principales: Hoffman, Kyle S., Chung, Christina Z., Mukai, Takahito, Krahn, Natalie, Jiang, Han-Kai, Balasuriya, Nileeka, O'Donoghue, Patrick, Söll, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573291/
https://www.ncbi.nlm.nih.gov/pubmed/37279998
http://dx.doi.org/10.1261/rna.079658.123