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New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement

Radiation therapy is an essential component of present-day cancer management, utilizing ionizing radiation (IR) of different modalities to mitigate cancer progression. IR functions by generating ionizations in cells that induce a plethora of DNA lesions. The most detrimental among them are the DNA d...

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Detalles Bibliográficos
Autores principales: Mladenov, Emil, Mladenova, Veronika, Stuschke, Martin, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573367/
https://www.ncbi.nlm.nih.gov/pubmed/37834403
http://dx.doi.org/10.3390/ijms241914956