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Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells

Glioblastoma (GBM) is the most lethal brain cancer, causing inevitable deaths of patients owing to frequent relapses of cancer stem cells (CSCs). The significance of the NOTCH signaling pathway in CSCs has been well recognized; however, there is no NOTCH-selective treatment applicable to patients wi...

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Detalles Bibliográficos
Autores principales: Ham, Seok Won, Kim, Jung Yun, Seo, Sunyoung, Hong, Nayoung, Park, Min Ji, Kim, Yoonji, Jang, Junseok, Park, Sehyeon, Lee, Silvee Jisoo, Kim, Jun-Kyum, Kim, Eun-Jung, Kim, Sung-Ok, Kim, Sung-Chan, Park, Jong-Whi, Kim, Hyunggee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573421/
https://www.ncbi.nlm.nih.gov/pubmed/37834227
http://dx.doi.org/10.3390/ijms241914776