OGR1 (GPR68) and TDAG8 (GPR65) Have Antagonistic Effects in Models of Colonic Inflammation

G-protein-coupled receptors (GPRs), including pro-inflammatory ovarian cancer GPR1 (OGR1/GPR68) and anti-inflammatory T cell death-associated gene 8 (TDAG8/GPR65), are involved in pH sensing and linked to inflammatory bowel disease (IBD). OGR1 and TDAG8 show opposite effects. To determine which effe...

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Detalles Bibliográficos
Autores principales: Perren, Leonie, Busch, Moana, Schuler, Cordelia, Ruiz, Pedro A., Foti, Federica, Weibel, Nathalie, de Vallière, Cheryl, Morsy, Yasser, Seuwen, Klaus, Hausmann, Martin, Rogler, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573511/
https://www.ncbi.nlm.nih.gov/pubmed/37834303
http://dx.doi.org/10.3390/ijms241914855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573511/
https://www.ncbi.nlm.nih.gov/pubmed/37834303
http://dx.doi.org/10.3390/ijms241914855

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