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Unveiling Novel Avenues in mTOR-Targeted Therapeutics: Advancements in Glioblastoma Treatment

The mTOR signaling pathway plays a pivotal and intricate role in the pathogenesis of glioblastoma, driving tumorigenesis and proliferation. Mutations or deletions in the PTEN gene constitutively activate the mTOR pathway by expressing growth factors EGF and PDGF, which activate their respective rece...

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Detalles Bibliográficos
Autores principales: Singh, Shilpi, Barik, Debashis, Lawrie, Karl, Mohapatra, Iteeshree, Prasad, Sujata, Naqvi, Afsar R., Singh, Amar, Singh, Gatikrushna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573615/
https://www.ncbi.nlm.nih.gov/pubmed/37834408
http://dx.doi.org/10.3390/ijms241914960