Synthesis and Antiviral and Antitumor Activities of Novel 18β-Glycyrrhetinic Acid Derivatives

A series of novel derivatives of 18β-glycyrrhetinic acid (GA) were synthesized by introducing aromatic or heterocyclic structures to extend the side chain, thereby enhancing their interaction with amino acid residues in the active pocket of the target protein. These compounds were structurally chara...

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Detalles Bibliográficos
Autores principales: Pan, Bo-Wen, Zheng, Liang-Liang, Shi, Yang, Dong, Zhang-Chao, Feng, Ting-Ting, Yang, Jian, Wei, Ying, Zhou, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573640/
https://www.ncbi.nlm.nih.gov/pubmed/37834459
http://dx.doi.org/10.3390/ijms241915012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573640/
https://www.ncbi.nlm.nih.gov/pubmed/37834459
http://dx.doi.org/10.3390/ijms241915012

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