Cargando…
Synthesis and Antiviral and Antitumor Activities of Novel 18β-Glycyrrhetinic Acid Derivatives
A series of novel derivatives of 18β-glycyrrhetinic acid (GA) were synthesized by introducing aromatic or heterocyclic structures to extend the side chain, thereby enhancing their interaction with amino acid residues in the active pocket of the target protein. These compounds were structurally chara...
Autores principales: | Pan, Bo-Wen, Zheng, Liang-Liang, Shi, Yang, Dong, Zhang-Chao, Feng, Ting-Ting, Yang, Jian, Wei, Ying, Zhou, Ying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573640/ https://www.ncbi.nlm.nih.gov/pubmed/37834459 http://dx.doi.org/10.3390/ijms241915012 |
Ejemplares similares
-
Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid
por: Cai, Dong, et al.
Publicado: (2020) -
Synthesis, Antiviral, and Antibacterial Activity of the Glycyrrhizic Acid and Glycyrrhetinic Acid Derivatives
por: Mohammed, E. A. H., et al.
Publicado: (2022) -
An Overview of Structurally Modified Glycyrrhetinic Acid Derivatives as Antitumor Agents
por: Xu, Bing, et al.
Publicado: (2017) -
Synthesis and Anticancer Activities of Glycyrrhetinic Acid Derivatives
por: Li, Yang, et al.
Publicado: (2016) -
Design, synthesis and biological evaluation of novel amide-linked 18β-glycyrrhetinic acid derivatives as novel ALK inhibitors
por: Cai, Dong, et al.
Publicado: (2020)