METTL3-Mediated RNA m(6)A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2

PURPOSE: N(6)-methyladenosine (m(6)A) is a commonly occurring modification of mRNAs, catalyzed by a complex containing methyltransferase like 3 (METTL3). Our research aims to explore how METTL3-dependent m(6)A modification affects the functions of retinal endothelial cells (RECs). METHODS: An oxygen...

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Detalles Bibliográficos
Autores principales: Lin, Yong, Luo, Guangying, Liu, Qi, Yang, Rusen, Sol Reinach, Peter, Yan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573643/
https://www.ncbi.nlm.nih.gov/pubmed/37819742
http://dx.doi.org/10.1167/iovs.64.13.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573643/
https://www.ncbi.nlm.nih.gov/pubmed/37819742
http://dx.doi.org/10.1167/iovs.64.13.18

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