New Benzamides as Multi-Targeted Compounds: A Study on Synthesis, AChE and BACE1 Inhibitory Activity and Molecular Docking

The synthesis of eleven new and previously undescribed benzamides was designed. These compounds were specifically projected as potential inhibitors of the enzymes acetylcholinesterase (AChE) and β-secretase (BACE1). N,N′-(1,4-phenylene)bis(3-methoxybenzamide) was most active against AChE, with an in...

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Detalles Bibliográficos
Autores principales: Drozdowska, Danuta, Maliszewski, Dawid, Wróbel, Agnieszka, Ratkiewicz, Artur, Sienkiewicz, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573752/
https://www.ncbi.nlm.nih.gov/pubmed/37834347
http://dx.doi.org/10.3390/ijms241914901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573752/
https://www.ncbi.nlm.nih.gov/pubmed/37834347
http://dx.doi.org/10.3390/ijms241914901

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