The cGAS/STING/IFN-1 Response in Squamous Head and Neck Cancer Cells after Genotoxic Challenges and Abrogation of the ATR-Chk1 and Fanconi Anemia Axis

Locally advanced head and neck squamous cell carcinomas (HNSCC) are often refractory to platinum-based radiochemotherapy and new immuno-oncological strategies. To stimulate immunogenic antitumor responses in HNSCC patients, we investigated the cGAS/STING/IFN-1 signaling pathway after genotoxic treat...

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Detalles Bibliográficos
Autores principales: Zahnreich, Sebastian, El Guerzyfy, Soumia, Kaufmann, Justus, Schmidberger, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573837/
https://www.ncbi.nlm.nih.gov/pubmed/37834346
http://dx.doi.org/10.3390/ijms241914900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573837/
https://www.ncbi.nlm.nih.gov/pubmed/37834346
http://dx.doi.org/10.3390/ijms241914900

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