Antiviral Efficacy of RNase H-Dependent Gapmer Antisense Oligonucleotides against Japanese Encephalitis Virus

RNase H-dependent gapmer antisense oligonucleotides (ASOs) are a promising therapeutic approach via sequence-specific binding to and degrading target RNAs. However, the efficacy and mechanism of antiviral gapmer ASOs have remained unclear. Here, we investigated the inhibitory effects of gapmer ASOs...

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Detalles Bibliográficos
Autores principales: Okamoto, Shunsuke, Echigoya, Yusuke, Tago, Ayaka, Segawa, Takao, Sato, Yukita, Itou, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573891/
https://www.ncbi.nlm.nih.gov/pubmed/37834294
http://dx.doi.org/10.3390/ijms241914846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573891/
https://www.ncbi.nlm.nih.gov/pubmed/37834294
http://dx.doi.org/10.3390/ijms241914846

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