RNA-Based Strategies for Cancer Therapy: In Silico Design and Evaluation of ASOs for Targeted Exon Skipping

Precision medicine in oncology has made significant progress in recent years by approving drugs that target specific genetic mutations. However, many cancer driver genes remain challenging to pharmacologically target (“undruggable”). To tackle this issue, RNA-based methods like antisense oligonucleo...

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Detalles Bibliográficos
Autores principales: Pacelli, Chiara, Rossi, Alice, Milella, Michele, Colombo, Teresa, Le Pera, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573945/
https://www.ncbi.nlm.nih.gov/pubmed/37834310
http://dx.doi.org/10.3390/ijms241914862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573945/
https://www.ncbi.nlm.nih.gov/pubmed/37834310
http://dx.doi.org/10.3390/ijms241914862

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