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RNA-Based Strategies for Cancer Therapy: In Silico Design and Evaluation of ASOs for Targeted Exon Skipping
Precision medicine in oncology has made significant progress in recent years by approving drugs that target specific genetic mutations. However, many cancer driver genes remain challenging to pharmacologically target (“undruggable”). To tackle this issue, RNA-based methods like antisense oligonucleo...
Autores principales: | Pacelli, Chiara, Rossi, Alice, Milella, Michele, Colombo, Teresa, Le Pera, Loredana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573945/ https://www.ncbi.nlm.nih.gov/pubmed/37834310 http://dx.doi.org/10.3390/ijms241914862 |
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