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Enhancing Giardicidal Activity and Aqueous Solubility through the Development of “RetroABZ”, a Regioisomer of Albendazole: In Vitro, In Vivo, and In Silico Studies †

Parasitic diseases, including giardiasis caused by Giardia lamblia (G. lamblia), present a considerable global health burden. The limited effectiveness and adverse effects of current treatment options underscore the necessity for novel therapeutic compounds. In this study, we employed a rational des...

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Detalles Bibliográficos
Autores principales: Martínez-Conde, Carlos, Colín-Lozano, Blanca, Gutiérrez-Hernández, Abraham, Hernández-Núñez, Emanuel, Yépez-Mulia, Lilián, Colorado-Pablo, Luis Fernando, Aguayo-Ortiz, Rodrigo, Escalante, Jaime, Rivera-Leyva, Julio C., Sánchez-Carranza, Jessica Nayelli, Barbosa-Cabrera, Elizabeth, Navarrete-Vazquez, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573946/
https://www.ncbi.nlm.nih.gov/pubmed/37834396
http://dx.doi.org/10.3390/ijms241914949