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Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil

Single-stranded DNA-binding proteins (SSBs) play a crucial role in DNA metabolism by binding and stabilizing single-stranded DNA (ssDNA) intermediates. Through their multifaceted roles in DNA replication, recombination, repair, replication restart, and other cellular processes, SSB emerges as a cent...

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Detalles Bibliográficos
Autores principales: Su, Hsin-Hui, Huang, Yen-Hua, Lien, Yi, Yang, Po-Chun, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573954/
https://www.ncbi.nlm.nih.gov/pubmed/37834349
http://dx.doi.org/10.3390/ijms241914899