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Aggregation, Transmission, and Toxicity of the Microtubule-Associated Protein Tau: A Complex Comprehension

The microtubule-associated protein tau is an intrinsically disordered protein containing a few short and transient secondary structures. Tau physiologically associates with microtubules (MTs) for its stabilization and detaches from MTs to regulate its dynamics. Under pathological conditions, tau is...

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Detalles Bibliográficos
Autores principales: Hu, Jiaxin, Sha, Wenchi, Yuan, Shuangshuang, Wu, Jiarui, Huang, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573976/
https://www.ncbi.nlm.nih.gov/pubmed/37834471
http://dx.doi.org/10.3390/ijms241915023