Sleeping Beauty Transposon Insertions into Nucleolar DNA by an Engineered Transposase Localized in the Nucleolus

Transposons are nature’s gene delivery vehicles that can be harnessed for experimental and therapeutic purposes. The Sleeping Beauty (SB) transposon shows efficient transposition and long-term transgene expression in human cells, and is currently under clinical development for gene therapy. SB trans...

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Detalles Bibliográficos
Autores principales: Kovač, Adrian, Miskey, Csaba, Ivics, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573994/
https://www.ncbi.nlm.nih.gov/pubmed/37834425
http://dx.doi.org/10.3390/ijms241914978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573994/
https://www.ncbi.nlm.nih.gov/pubmed/37834425
http://dx.doi.org/10.3390/ijms241914978

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