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Two Different Isocitrate Dehydrogenases from Pseudomonas aeruginosa: Enzymology and Coenzyme-Evolutionary Implications

Pseudomonas aeruginosa PAO1, as an experimental model for Gram-negative bacteria, harbors two NADP(+)-dependent isocitrate dehydrogenases (NADP-IDHs) that were evolved from its ancient counterpart NAD-IDHs. For a better understanding of PaIDH1 and PaIDH2, we cloned the genes, overexpressed them in E...

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Detalles Bibliográficos
Autores principales: Chen, Xuefei, Wei, Wei, Xiong, Wei, Wu, Shen, Wu, Quanchao, Wang, Peng, Zhu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574006/
https://www.ncbi.nlm.nih.gov/pubmed/37834433
http://dx.doi.org/10.3390/ijms241914985