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Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

The pathophysiology of chronic kidney disease-mineral and bone disorder (CKD-MBD) is not well understood. Specific factors secreted by osteocytes are elevated in the serum of adults and pediatric patients with CKD-MBD, including FGF-23 and sclerostin, a known inhibitor of the Wnt signaling pathway....

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Detalles Bibliográficos
Autores principales: Laster, Marciana, Pereira, Renata C., Noche, Kathleen, Gales, Barbara, Salusky, Isidro B., Albrecht, Lauren V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574198/
https://www.ncbi.nlm.nih.gov/pubmed/37836411
http://dx.doi.org/10.3390/nu15194127