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Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity

Bitter taste receptors (Tas2rs in mice) detect bitterness, a warning signal for toxins and poisons, and are expressed in enteroendocrine cells. We tested the hypothesis that Tas2r138 and Tas2r116 mRNAs are modulated by microbiota alterations induced by a long-term high-fat diet (HFD) and antibiotics...

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Detalles Bibliográficos
Autores principales: Caremoli, Filippo, Huynh, Jennifer, Lagishetty, Venu, Markovic, Daniela, Braun, Jonathan, Dong, Tien S., Jacobs, Jonathan P., Sternini, Catia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574285/
https://www.ncbi.nlm.nih.gov/pubmed/37836428
http://dx.doi.org/10.3390/nu15194145