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Discovery of Novel Mono-Carbonyl Curcumin Derivatives as Potential Anti-Hepatoma Agents

Curcumin possesses a wide spectrum of liver cancer inhibition effects, yet it has chemical instability and poor metabolic properties as a drug candidate. To alleviate these problems, a series of new mono-carbonyl curcumin derivatives G1–G7 were designed, synthesized, and evaluated by in vitro and in...

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Detalles Bibliográficos
Autores principales: Cao, Weiya, Yu, Pan, Yang, Shilong, Li, Zheyu, Zhang, Qixuan, Liu, Zengge, Li, Hongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574324/
https://www.ncbi.nlm.nih.gov/pubmed/37836639
http://dx.doi.org/10.3390/molecules28196796