First-Row Transition Metal Complexes Incorporating the 2-(2′-pyridyl)quinoxaline Ligand (pqx), as Potent Inflammatory Mediators: Cytotoxic Properties and Biological Activities against the Platelet-Activating Factor (PAF) and Thrombin

Inflammatory mediators constitute a recently coined term in the field of metal-based complexes with antiplatelet activities. Our strategy targets Platelet-Activating Factor (PAF) and its receptor, which is the most potent lipid mediator of inflammation. Thus, the antiplatelet (anti-PAF) potency of a...

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Detalles Bibliográficos
Autores principales: Margariti, Antigoni, Papakonstantinou, Vasiliki D., Stamatakis, George M., Demopoulos, Constantinos A., Machalia, Christina, Emmanouilidou, Evangelia, Schnakenburg, Gregor, Nika, Maria-Christina, Thomaidis, Nikolaos S., Philippopoulos, Athanassios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574351/
https://www.ncbi.nlm.nih.gov/pubmed/37836742
http://dx.doi.org/10.3390/molecules28196899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574351/
https://www.ncbi.nlm.nih.gov/pubmed/37836742
http://dx.doi.org/10.3390/molecules28196899

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