Cargando…

Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine Analogs

In the current study, we described the synthesis of ten new 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine analogs (4a–j), as well as their characterization, anticancer activity, molecular docking studies, ADME, and toxicity prediction. The title compounds (4a–j) were prepared in three steps, sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahsan, Mohamed Jawed, Gautam, Krishna, Ali, Amena, Ali, Abuzer, Altamimi, Abdulmalik Saleh Alfawaz, Salahuddin, Alossaimi, Manal A., Lakshmi, S. V. V. N. S. M., Ahsan, Md. Faiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574406/
https://www.ncbi.nlm.nih.gov/pubmed/37836779
http://dx.doi.org/10.3390/molecules28196936