Formation of 5-Aminomethyl-2,3-dihydropyridine-4(1H)-ones from 4-Amino-tetrahydropyridinylidene Salts

Various 4-aminotetrahydropyridinylidene salts were treated with aldehydes in an alkaline medium. Their conversion to 5-substituted β-hydroxyketones in a one-step reaction succeeded only with an aliphatic aldehyde. Instead, aromatic aldehydes gave 5-substituted β-aminoketones or a single δ-diketone....

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Detalles Bibliográficos
Autores principales: Seebacher, Werner, Hoffelner, Michael, Belaj, Ferdinand, Pirker, Teresa, Alajlani, Muaaz, Bauer, Rudolf, Pferschy-Wenzig, Eva-Maria, Saf, Robert, Weis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574582/
https://www.ncbi.nlm.nih.gov/pubmed/37836712
http://dx.doi.org/10.3390/molecules28196869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574582/
https://www.ncbi.nlm.nih.gov/pubmed/37836712
http://dx.doi.org/10.3390/molecules28196869

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