Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity

A new series of spirooxindoles based on benzimidazole, triazole, and isatin moieties were synthesized via a [3+2] cycloaddition reaction protocol in one step. The single X-ray crystal structure of the intermediate triazole-benzimidazole 4 was solved. The new chemical structures of these spirooxindol...

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Detalles Bibliográficos
Autores principales: Alshahrani, Saeed, Al-Majid, Abdullah Mohammed, Alamary, Abdullah Saleh, Ali, Mohamed, Altowyan, Mezna Saleh, Ríos-Gutiérrez, Mar, Yousuf, Sammer, Barakat, Assem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574610/
https://www.ncbi.nlm.nih.gov/pubmed/37836817
http://dx.doi.org/10.3390/molecules28196976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574610/
https://www.ncbi.nlm.nih.gov/pubmed/37836817
http://dx.doi.org/10.3390/molecules28196976

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