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In Vitro Affinity Maturation of Nanobodies against Mpox Virus A29 Protein Based on Computer-Aided Design

Mpox virus (MPXV), the most pathogenic zoonotic orthopoxvirus, caused worldwide concern during the SARS-CoV-2 epidemic. Growing evidence suggests that the MPXV surface protein A29 could be a specific diagnostic marker for immunological detection. In this study, a fully synthetic phage display librar...

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Detalles Bibliográficos
Autores principales: Yu, Haiyang, Mao, Guanchao, Pei, Zhipeng, Cen, Jinfeng, Meng, Wenqi, Wang, Yunqin, Zhang, Shanshan, Li, Songling, Xu, Qingqiang, Sun, Mingxue, Xiao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574621/
https://www.ncbi.nlm.nih.gov/pubmed/37836685
http://dx.doi.org/10.3390/molecules28196838